A new study out of Australia suggests that Nicotinamide (aka Niacinamide, a cousin to Niacin, or Vitamin B3) may reduce the number of non-melanoma skin cancers in patients at risk for developing more. It was taken twice daily for a year.
All 386 study patients had had at least two non-melanoma skin cancers in the previous 5 years, so were at high risk for more basal cell and squamous cell carcinomas. At 12 months, the rate of new non-melanoma skin cancers was 23% lower in the nicotinamide group than in the placebo group (P = .02). Nicotinamide is over-the-counter, and has none of the flushing or gastrointestinal side-effects found with Niacin, which is used to reduce cholesterol and in other skin-related disorders. While the number of people involved in the trial was small, the results are significant, and the side-effects are virtually non-existent. Right now, it seems like a no-brainer for those who have had non-melanoma skin cancers in the past and continue to develop the rough skin-colored scaly actinic keratoses.
Barry I. Resnik, MD
Resnik Skin Institute
2630 NE 203 St #105
Aventura, FL 33180
Adult and Pediatric Dermatology and Cosmetic Surgery